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GABAA receptor agonist Gaboxadol Hydrochloride THIP CAS: 85118-33-8

Gaboxadol (or THIP) is a direct GABA mimetic ligand at delta-containing receptors. 
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Gaboxadol (or THIP) is a direct GABA mimetic ligand at delta-containing receptors. Gaboxadol went into human clinical trials to test if the drug promoted sleep. It was generally well tolerated. Gaboxadol enhances delta power in NREM sleep in humans. Gaboxadol failed in Phase III for sleep studies. The side effects of Gaboxadol have been described as mild and similar in quality to those of other GABA-mimetics. Gaboxadol is in development with Ovid Therapeutics as a treatment for Angelman syndrome, fragile X syndrome and epilepsy.


Product name: Gaboxadol Hydrochloride
CAS: 85118-33-8
MF: C6H9ClN2O2
MW: 176.60086
EINECS: 285-687-7
Purity: ≥99.0%
Appearance: white solid

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