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Trilostane is an inhibitor of 3 beta-hydroxysteroid dehydrogenase used in the treatment of Cushing's syndrome. It was withdrawn from the United States market in April 1994. It is a synthetic enzyme inhibiting drug that is used to treat Cushing’s disease in dogs and cats. Trilostane decreases the production of excessive cortisol hormone by the adrenal gland. This disease is not cured by trilostane but can be managed successfully.
Mechanism of action：
Trilostane produces suppression of the adrenal cortex by inhibiting enzymatic conversion of steroids by 3-beta-hydroxysteroid dehydrogenase/delta 5,4 ketosteroid isomerase, thus blocking synthesis of adrenal steroids.
Products Name: Trilostane
Brand Name:Vetoryl
CAS No.: 13647-35-3
Molecular Formula: C20H27NO3
Molecular Weight: 329.43g/mol
Specifition: 99%
Appearance: White Powder
Typical use: Treatments of Cushing's Disease
Standard Packing : 10gram,100gram,1kg
Shelf Life: 2 years
Storage: Room temperature away from light
Trilostane is an inhibitor of 3 beta-hydroxysteroid dehydrogenase used in the treatment of Cushing's syndrome. It was withdrawn from the United States market in April 1994. It is a synthetic enzyme inhibiting drug that is used to treat Cushing’s disease in dogs and cats. Trilostane decreases the production of excessive cortisol hormone by the adrenal gland. This disease is not cured by trilostane but can be managed successfully.
Mechanism of action：
Trilostane produces suppression of the adrenal cortex by inhibiting enzymatic conversion of steroids by 3-beta-hydroxysteroid dehydrogenase/delta 5,4 ketosteroid isomerase, thus blocking synthesis of adrenal steroids.
Products Name: Trilostane
Brand Name:Vetoryl
CAS No.: 13647-35-3
Molecular Formula: C20H27NO3
Molecular Weight: 329.43g/mol
Specifition: 99%
Appearance: White Powder
Typical use: Treatments of Cushing's Disease
Standard Packing : 10gram,100gram,1kg
Shelf Life: 2 years
Storage: Room temperature away from light